What is a "super pill?"
There is a long tradition of "super pills" in the Orient. Only the rarest of the rare formulations have been called a "super pill." A "super pill" is by definition a breakout formulation made from the most extraordinary materials, that tonifies all Three Treasures (Jing, Qi andShen), specifically promotes longevity, slows down aging, protects against many imbalanced conditions by supporting universal homeostasis, and enhances one's state of awareness. Usually, the preparation of a "super pill" is in its own right an exercise of the extreme technology of the era.
What is Super Pill No.2™?
Super Pill No.2™ is one of those rarest of the rare formulations. It is made from materials that are so rare and finely produced that the product is virtually non-duplicable by anyone else. Super Pill No.2™ has been produced with 100% naturally derived ingredients, extracted from the most powerful tonic herbs known to mankind. It is made using the most advanced nutraceutical technology in the world to assure potency, purity and efficacy. It has been designed to protect the fundamental processes of life from attack, destruction and aging. It protects our DNA and other cellular structures and functions from damage and premature degradation and aging, in numerous ways. Furthermore, all of the ingredients are remarkably safe for human consumption over an extended period of time.
Super Pill No.2™ is based simultaneously on both modern and traditional principles. It is based on cutting edge scientific research in the fields of longevity, cellular biology, biochemistry and aging.
Simultaneously, it is based on the sanctified traditions of Chinese tonic herbalism, the most sophisticated herbal system in the world. It has been produced with ingredients obtained from Di Tao sources acknowledged to be the best sources of each of the herbs, and manufactured using cutting edge pharmaceutical technologies, and by Fingerprint Identical Transfer Technology™ (FITT™), the most advanced herbal extraction technology in the world. With FITT™, the "fingerprint" of the finished extract is virtually identical to the fingerprint of the freshly harvested herb. That means, it contains all the same constituents in the same ratios. The smell, flavor and effect of herbs extracted by FITT™ are identical to that of the raw plant. But it is much more potent.
I have developed numerous tonic formulations, many using the ultimate herbs on earth. Many could be considered "super pills," but only one has previously received that special title. This formulation, however, stands out and deserves the title "Super Pill No.2™."
What's in Super Pill No.2™?
Super Pill No.2™ is composed of two cutting edge nutraceutical compounds, two "total component fractions" and five whole herb supertonic extracts (made by FITT™). These ingredients are woven together into a perfectly balanced formulation. Together, they make perfect sense in terms of the traditional Three Treasures System of Oriental herbalism, tonifying all three Treasures (Jing, Qi and Shen) and nurturing both Yin and Yang. All of the herbs, "total component fractions" and nutraceuticals are powerfully adaptogenic. Together, they assure optimum adaptive capacity at every level. That means optimized functioning at every level.
At the same time, the formula takes full account of the current major theories of aging, biology and biochemistry in the fields of genetics, aging, metabolic health and the physiology of aging and life extension.
- Astragaloside IV
- Total Astragalosides
- Total Gypenosides
- 100% PureTrans™ Resveratrol
- FITT™ full-spectrum whole herb extraction of the following elite adaptogenic herbs:
- Polygonum multiflorum
- 20 mg/cap (40 mg/dose)
- 20 mg/cap (40 mg/dose)
- 30 mg/cap (60 mg/dose)
- 90 mg/cap (180 mg/dose)
- 65 mg/cap (130 mg/dose)
- 65 mg/cap (130 mg/dose)
- 30 mg/cap (60 mg/dose)
- 30 mg/cap (60 mg/dose)
- 30 mg/cap (60 mg/dose)
Astragaloside IV (Astragalus membranaceus root saponin)
Astragaloside IV is one of the ultimate nutraceuticals developed in the world in the modern nutraceutical era. It has many functions, including most of those traditionally associated with Astragalus root. Astragalus has many active constituents. By far the most important constituents are a range of saponins known as astragalosides. Astragalus has more than fifty such saponins, known as astragalosides. Astragaloside IV has been acknowledged as the most potent and health promoting of the astragalosides, though many of the others have potent actions as well. Astragaloside IV is a potent immune modulating substance. It has been shown in human and animal studies to promote the normal, healthy functions of the immune system when consumed in the doses suggested for this formula. This dosage has been established by the inventors and subsequent researchers from the Chinese Academy of Medical Sciences. It has been used clinically in Asia for over fifteen years and its safety has been well established.* It may be used as a dietary supplement to promote normal, healthy functions and structural integrity.
Ron Teeguarden has been working on bringing an Astragaloside IV product to market since 1994. The original work on Astragaloside IV was done at China Pharmaceutical University in Nanjing China in the early 1990s. Ron purchased the rights to that research in 1995, and financially supported further Astragaloside research. The very first "standard" for Astragaloside IV in the world was produced by Ron's partners at that time. This original "standard" became the "standard" for the Chinese Academy of Medical Sciences and for the Chinese Pharmacopeia. In other words, all Astragaloside IV in the world is judged against that specific "standard." Due to cost issues of producing a refined Astragaloside IV product, the project has been on hold until recently. We are now extremely pleased to be bringing this incredible material to market in a “super pill” format.
Astragaloside IV is being investigated for its function as an antiaging substance. It appears that it may have the capacity to slow down and even reverse the loss of telomere length due to oxidative stress and the process of aging.
Telomeres are generally credited with maintaining the integrity of DNA by securing the ends of chromosomes. Telomeres are responsible for maintaining chromosomal stability and integrity. They do this by protecting the chromosome extremities from fusion and degradation. Telomeres also serve to camouflage chromosome ends from the "DNA damage response machinery." DNA damage response can be defined as a network of mechanisms that (1) sense, signal and repair DNA damage, and (2) regulate cell cycle progression and cell turnover. Without the telomeres, the mechanisms would perceive new chromosomes as defective.
Telomeres consist of a specific repetitive DNA sequence. As we age, with each replication of a cell, the telomeres become shorter, until eventually they no longer are functional and the cell enters into a phase known as cellular senescence. These old cells never replicate again and mistakes begin to accumulate at a brisk pace. Degeneration and aging of the whole body is the result.
Telomere length is widely believed to be a reliable marker for longevity in humans. But it is more than a mere "marker." Slowing down telomere loss is believed by many to slow down aging at the cellular level. There is considerable compelling evidence to support this theory.
As a result, a theory of aging has evolved known as the Telomere Theory of Cell Senescence and Aging. According to this theory, the key mechanism that drives cellular aging is the loss of telomeric DNA which will eventually cause chromosomal instability (Collado et al., 2007).
Telomerase is the unique enzyme able to elongate the ends of telomeres. Without telomerase, telomeres shorten. In the presence of telomerase, telomeres can maintain their healthy length. It is believed that Astragaloside IV is a mild telomerase "activator." A telomerase activator stimulates the enzyme telomerase that repairs telomeres and helps them maintain their youthful length.
Astragaloside IV is also being investigated (in the United States) for its neuro-regenerative capacity. Studies have shown that Astragaloside IV may be able to protect against degeneration of neurological cells and tissues in humans.
Astragaloside IV was first described in the Chinese Pharmacopeia in 1995 and has been used clinically in China since 1995 for a variety of anti-aging and immune-modulating purposes.
Astragaloside IV is in clinical use in China as a cardioprotective agent.
It has been demonstrated that the benefits of Astragaloside IV are significantly enhanced when combined with other Astragalus components, including the full spectrum of astragalosides known as Total Astragalosides. For that reason, Super Pill No. 2 contains an equal quantity of Astragaloside IV and Total Astragalosides. To assure that all components of high quality fresh Astragalus are present, a full spectrum Astragalus extract produced by FITT™ has been added so that no cofactor is left out of the formula.
Total Astragalosides (Astragalus membranaceus root saponins)
Astragalus contains over fifty known astragalosides, which are saponins that have a water soluble end and a fat soluble end. Saponins are major constituents of many of the ultimate tonic herbs, including ginseng, rhodiola, eleuthero and gynostemma. The Total Astragaloside Fraction consists of ALL of the astragalosides naturally occurring in Astragalus root. Numerous studies have shown that this Total Astragaloside Fraction has numerous powerful health benefits. The original work on the Total Astragaloside Fraction was done at China Pharmaceutical University in Nanjing China in the early 1990s. Ron purchased the rights to that research in 1995, and financially supported further Astragaloside research. The Total Astragaloside Fraction is a very potent antioxidant. Each capsule of Super Pill No.2™ contains 30 mg of purified Total Astragalosides. This is a very potent dose. This is to increase the potency of the formulation and to support the actions of Astragaloside IV. The Total Astragaloside Fraction is very safe for human consumption.
Gypenosides (Gynostemma pentaphyllum leaf saponins)
Gypenosides are the main active constituents of Gynostemma pentaphyllum, an herbaceous vine that grows in semi tropical mountains in central and southern China. Gynostemma is one of the premier antiaging tonic herbs used in Chinese herbalism. It is a very effective broad spectrum anti-inflammatory and has no known side effects. It may be consumed daily for a lifetime. It is widely used in Asia as a general tonic. It is also widely used to reduce chronic low grade inflammation ("false fire"). Gynostemma is believed to slow down "inflammaging," the chronic inflammation-caused root of most aging in the human body. The Gypenosides, which are the primary active constituents of Gynostemma are saponins similar to those found in Ginseng and Astragalus. The Gypenosides have the most impact on inflammation, especially when combined with FITT Gynostemma extract, which is a full spectrum extract of the entire herb. The pure Gypenosides are the richest possible source of Gypenoside XLIX (49), believed to be the most potent antiaging component of Gynostemma, similar to Astragaloside IV.
Gypenoside XLIX has been demonstrated to counteract the deleterious effects of Nuclear Factor Kappa B (NFkB), the substance at the root of all inflammation in all vertebrates and involved in most cell death in animals. Reducing the activity of Nuclear Factor Kappa B should be one of the goals of any longevity, antiaging program. This compound promotes aging and is at the center of all research into life extension. Gynostemma's broad reputation as a longevity herb is certainly based on this ability to quell Nuclear Factor Kappa B.
Gypenoside XLIX has been shown in a rat study to be able to reverse the aging of skin, returning the skin of aged rats to that of young rats. This is the first result of this kind in science. This is the effect attributed to Gynostemma by millions of Chinese people who consume it regularly.
Gypenosides are safe for the liver. They are in fact powerful liver protectors. Studies indicate that Gypenosides can help prevent nonalcoholic and alcohol-induced fatty liver.
Gynostemma is one of the most popular tonic herbs in the world and this product contains the most potent form, being a blend of pure Gypenosides and FITT™ full spectrum Gynostemma extract.
Resveratrol (100% PureTrans)
Resveratrol is one of the most important nutraceuticals in the world today. It is a polyphenol molecule found in many plant species including grapes, peanuts, cranberries, Polygonum cuspidatum and others. Polyphenols are common in the human diet (at least among those who eat a healthy diet), where they act as antioxidants. In the plant, they act as antioxidants and protect against free radical damage by bacteria, fungi and UV radiation.
Resveratrol exerts anti-aging effects in animals. Numerous studies have shown resveratrol has potent antioxidant and anti-inflammatory effects, promotes vascular endothelial function, enhances lipid metabolism and has anti-cancer activity. It appears that resveratrol has numerous mechanisms by which it exerts its effects on the human body.
It’s anti-inflammatory actions are of great importance to slowing down aging and preventing degenerative disorders associated with aging. In particular, it inhibits NFkB signaling, which in turn down-regulates inflammatory cytokine expression in our cells. Inflammatory cytokines are the chemicals that stimulate inflammation in the body. When these cytokines are inhibited, there is less chronic inflammation in the tissues of the body. Resveratrol plays a powerful role in immune regulation by significantly inhibiting the secretion of numerous cytokines that cause inflammation, resulting in degeneration.
Resveratrol exerts powerful vascular support. Resveratrol can inhibit C-reactive protein (CRP). CRP is a non-specific inflammatory compound that is increased in acute and chronic inflammation and is a confirmed clinical "marker" of cardiovascular risk. Increased CRP can induce vascular endothelial dysfunction and promote atherosclerosis. Daily intake of Resveratrol may be able to inhibit this deleterious activity within the vascular system.
Resveratrol is being widely investigated for its proposed ability to improve cerebral blood flow, an important component of cognitive function. Reduction in cerebral blood flow is a well established cause of reduced cognitive function. Human studies have shown that Resveratrol quickly improves blood circulation.
Resveratrol supplementation in studies of mice fed high-fat diets demonstrated an inhibition of fat deposition in abdominal organs and an increase in insulin sensitivity, compared to control mice. Many studies seem to indicate that this ability to regulate fat metabolism is key to the ability of Resveratrol to prolong life in most animals.
Resveratrol is not only safe for the liver, but is actually a powerful liver protector. Studies indicate that Resveratrol can help prevent nonalcoholic and alcohol-induced fatty liver.
Current research indicates that a daily dosage in humans of 100 – 400 mg of trans-resveratrol may be of benefit in inflammatory conditions, to support healthy metabolic functions, as an anti-aging agent, to protect the cardiovascular system and for many other reasons.
It is widely believed that consuming Resveratrol with other anti-inflammatory antioxidants enhances the positive actions of Resveratrol, reduces the possibility of any side effects (minimal to start with), and reduces the quantity of Resveratrol required to be effective.
Astragaloside IV, Total Astragalosides, Gypenosides and Resveratrol work synergistically together to promote chronic anti-inflammatory actions in the body and as a powerful antioxidant that functions down to the nuclear level.
FITT Super-Adaptogen Extract Complex
Fingerprint Identity Transfer Technology™
How does the FITT™ process work?
FITT™ is a proprietary cutting-edge high-technology process, recently developed by the Chinese Academy of Medical Sciences, that utilizes physical forces to break the raw materials down to the micron level. The materials are "shaken" loose at tremendous speed, resulting in instantaneous extraction of both water-soluble and alcohol-soluble components from the raw material into the natural solvent (water and/or alcohol). The entire process is performed at a low to moderate temperature that never exceeds 40° C (104° F), thus eliminating the drawbacks of a heated extraction.
The characteristics of FITT™ technology
FITT™ extracts are really "raw" extracts.
Many people now understand that the raw, natural constituents of plants and other edible substances have special value in our bodies, but only if they are bio-available. Eating a raw herb is often futile because many herbs are indigestible by humans unless cooked, fermented or extracted. FITT™ accomplishes something very important for those who appreciate the value of raw foods and herbs. With the entire process’s temperature controlled under 104° F, FITT™ extracts are really "raw" extracts. FITT™ extracts the natural living constituents without damaging them in any way. In fact, far more constituents are released than are released by conventional extraction.
FITT™ technology captures the original phyto-chemical profile (the "fingerprint") of a botanical and transfers it safely and almost identically into the final extract, perfectly preserving the aroma, color and taste of the freshly collected botanical. In other words, the chemical profile is essentially identical to that of the living botanical.
- FITT™ technology is highly effective at extracting the active ingredients.
- The raw materials are processed to nearly micron level for maximum absorption efficiency.
- The entire extraction process does not exceed 104° Fahrenheit (boiling is 212° F). This relatively low extraction temperature ensures that all of the active constituents, including volatile components such as essential oils and enzymatic proteins, are preserved. This is in contrast to heated extraction technologies. During a heated extraction, some active ingredients are either destroyed or broken-down into different compounds.
FITT is a very green technology.
- FITT was developed specifically as a green technology.
- FITT technology uses 33% less energy than traditional extraction methods.
- FITT technology produces 1/20 the waste of home brewing, and about 1/7 the waste of traditional extraction. This means FITT technology needs much less raw materials to produce the same result, hence a much smaller carbon footprint.
- Zero waste of the production residue. With FITT, the residue makes perfect animal feed and organic fertilizer. Most of our production residue is donated to the local farms and is considered "organic."
- Most of the production water is recycled and only clean, filtered water is discharged.
Less raw materials, less energy consumption, recycled production water and automation of the entire production flow all contribute to a lower cost to produce the same amount of active ingredients, making FITT™ ingredients very economical and affordable. You get the highest potency, activity and benefits for the least cost, which is by definition "high value."
Rhodiola sacra root extract
Tibetan Rhodiola (Rhodiola sacra root) is an extraordinary herb. It is a relatively rare substance that grows in one of the harshest environments in the world. In the Orient, it is called "Plateau Ginseng," and the Tibetans considered Rhodiola to be a sacred herb. It has been used by the Tibetan people as a powerful adaptogenic vitalizer since the beginning of Tibetan civilization. Rhodiola has also been prized by the Chinese and was very positively reviewed in the first Chinese herbal classic over two thousand years ago. It was regarded as a life-prolonging, wisdom enhancing "superior herb." However, the rarity of Tibetan Rhodiola has prevented it from becoming a well-known commodity outside of Asia. This incredible herb was used by the Tibetan monks to enhance their inner spiritual power, the power of concentration and physical endurance. It has undoubtedly played a major role in the development of Tibetan culture.
Tibetan Rhodiola is a superb herb for people who work very hard, either physically or mentally. Tibetan Rhodiola has been shown to improve endurance and mental capacity, including memory enhancement. It has been shown to be a superb tonic and energizer for those into physical fitness, and a superior tonic for those stuck behind a desk or at a computer terminal for long periods of time.
Tibetan Rhodiola is especially beneficial to those who live under stressful conditions. It has been proven that Tibetan Rhodiola reduces the body’s stress reactions, and thus relieves mental stress as well. People stay focused and suffer far less from fatigue even under severe stress. It is the ideal herbal supplement for the modern world.
Tibetan Rhodiola has been found to be extremely beneficial to the cardiovascular system, and has been found to have potent cardioprotective benefits. It is also a powerful immune modulator, building the immune system into a well tuned fighting machine.
Consumption of a small amount of Rhodiola extract significantly improves a person’s capacity to absorb and utilize oxygen.
The main active constituent of Rhodiola is salidroside, a saponin related to those of Gynostemma and Astragalus. Salidroside and salidroside-like compounds are considered to be the most critical constitutes responsible for the multiple therapeutic, antiaging and health protecting benefits of Rhodiola. Salidroside protects human fibroblast cells from premature senescence induced by H2O2 partly through modulating oxidative status Salidroside protects neuronal PC12 cells from Abeta-induced cytotoxicity via its antioxidant pathway.
Rhodiola sacra (water and methanol extracts) showed strong scavenging activity against superoxide anion radical (*O2-), These active-oxygen scavengers may contribute to their anti-aging action.
In a premature-senescence model in human fetal lung fibroblasts, it was found that salidroside considerably reversed senescence-like phenotypes in the oxidant challenged model, including alterations of morphology and cell cycle, and protecting against DNA damage. The antioxidant property of salidroside was confirmed in this cellular system, and thus at least partially accounted for the protection of the compound against premature senescence. Similar protection of salidroside against replicative senescence was observed as well. The regulation of senescence-related molecules by salidroside also involved mechanisms that did not rely on its antioxidant activity. This finding presents salidroside as an agent with potential to retard aging and attenuate age-related diseases in humans.
The alcoholic and aqueous extracts of Rhodiola have marked cytoprotective and antioxidant activities. FITT Rhodiola contains both water soluble and alcohol soluble components of the raw herb.
Astragalus membranaceus root extract
One of the most important herbs in the world, Astragalus root (Astragalus membranaceus) has been recognized as a superb and potent immune system tonic by modern researchers. Astragalus has been used for over 2000 years to strengthen the body as a whole. Astragalus is believed by the Oriental people to improve metabolic, respiratory and immune functions.
Astragalus is said to have an effect on the "surface" of the body --- that is, it is used to tonify the "Protective Qi," known as Wei Qi in Chinese. This Protective Qi is a special kind of energy which circulates just under the skin and in the muscle. Protective Qi is a Yang energy. Protective Qi circulates in the subcutaneous tissues providing suppleness to the flesh and adaptive energy to the skin. This function is essential to life.
An important effect of Astragalus is in its ability to fortify the "Upright Qi." Upright Qi is the energy allocated by the body to maintain upright posture and to maintain the position of the organs in their healthy position in their battle with gravity. As one gets older, or if one experiences chronic fatigue or exhaustion, or during illness, this Upright Qi is easily depleted resulting in the sinking, or "prolapse," of organs.
Astragalus enhances the function of the skin to eliminate toxins. It is commonly used to help sores in the skin to come to a head and suppurate, and thus to heal more quickly and effectively.
Astragalus has a mild diuretic action and helps to relieve excessive sweating. It is helpful in treating loose stools, chronic diarrhea and chronic or recurring colds. If a cold lasts too long it can cause a general fatigue syndrome that can itself become chronic. Astragalus is very useful for people who just can’t seem to shake a cold, and Astragalus can replace the Qi necessary to regain full strength.
An interesting new area of research on Astragalus concerns its potential as a male fertility agent. Astragalus has been proved to stimulate sperm motility.
The FITT extract of Astragalus root assures that EVERY component of Astragalus root is in Super Pill No.2™. which assures total functioning of this herb in the body.
Panax Ginseng root extract
Asian Ginseng is one of the most famous and valued herbs used by mankind, Panax Ginseng is an energy tonic that regulates the human energy system. It has been shown to be both sedative and stimulating, regulatory to both the central nervous system and to the endocrine system. It is the primary Qi tonic of Chinese tonic herbalism.
Ginseng helps a person to adapt to all kinds of stresses, and enhances endurance and resilience under stressful conditions. It has thus been termed an "adaptogenic" substance by scientific researchers. Ginseng is also used to tonify digestive and respiratory functions. Ginseng contains many active ingredients, but the most important are the saponins called ginsenosides. Ginsenosides specifically improve adaptability and are believed to help build muscle and endurance. Therefore Ginseng is very popular with athletes. Ginseng generally has a "warm" energy.
Gynostemma pentaphyllum leaf extract
Gynostemma is widely believed in Asia to be an anti-aging, longevity herb. Gynostemma is generally reinforcing to overall health, has a strong anti-fatigue effect. It is also used throughout the Orient as a virtual "cure-all." Gynostemma is a major adaptogenic herb, in the same league as Panax Ginseng and Astragalus.
In China, Gynostemma is widely believed to reduce oxygen deficiency at high altitudes, to improve digestion, to strengthen the mind, and to improve sex functions. It is also believed to help calm the nerves and to ease pain.
The ultimate greatness of Gynostemma lies in its broad spectrum adaptogenic quality. It has double-direction activity in many areas. It has the ability to bring balance to the body under a wide range of stressful circumstances. Constant consumption of Gynostemma tends to have a highly protective quality because it strengthens the adaptive capacity of the person at every level of their life. The chemical constituents responsible for the adaptogenic characteristic of Gynostemma are saponins called gypenosides.
Gynostemma contains more than one hundred different gypenosides. This is the broadest range of saponins in one plant in nature. Ginseng, for example has about forty known saponins (ginsenosides) and Astragalus has about fifty known saponins (astragalosides). These gypenosides are very similar to that of Ginseng. In fact, four of Gynostemma’s saponins are precisely the same chemical structure as the saponins found in Ginseng and eleven more are almost identical. The similarities are so close and so extensive that Gynostemma is now called "Southern Ginseng." To the local people who grow it and consume it, it is simply called "Magical Grass."
Studies indicate that Gynostemma has a double-direction, regulating, and adaptogenic influence of the central nervous system. It is calming when one is overexcited and stimulating when one is depressed.
The FITT full spectrum extract of Gynostemma is used in this formula to assure complete compositional integrity of Super Pill No.2. Every component of Gynostemma is in this formula, with an emphasis on the Total Gypenoside Fraction.
Gynostemma leaf is the main ingredient in Spring Dragon Longevity Tea.
Polygonum multiflorum root extract (He Shou Wu root)
These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, or cure any disease.